Bachelor in mechanical engineering and master in biomedical engineering

Gabriele Nasello.

Position: PhD candidate, University of Zaragoza – KU Leuven

I am curious individual, eager to learn and to face new experiences. During my doctoral programme in biomedical engineering, jointly supervised by academia (University of Zaragoza, KU Leuven) and non-academic company (Materialise NV), I am applying the principles of bone tissue engineering to the development of a new generation of patient-specific implants, based on the implementation of bone regeneration computational models and the evaluation of the biologic response of bone tissue with in vitro experiments.


– Patient-specific bone-on-chips

– Computational models of mechano-driven bone regeneration

– Tissue engineering

– Organ-on-chip

– Computational modelling

– Image Processing

Mechano-driven regeneration predicts response variations in large animal model based on scaffold implantation site and individual mechano-sensitivity. 

Nasello, G., Vautrin, A., Pitocchi, J., Wesseling, M., Kuiper, J.H., Pérez, M.Á. and García-Aznar, J.M.,

Bone, 144, p.115769. (doi 10.1016/j.bone.2020.115769)


Primary human osteoblasts cultured in a 3D microenvironment create a unique representative model of their differentiation into osteocytes.

Nasello, G., Alamán-Díez, P., Schiavi, J., Pérez, M.Á., McNamara, L. and García-Aznar, J.M., 2020.

 Frontiers in Bioengineering and Biotechnology, 8, p.336. (doi 10.3389/fbioe.2020.00336)


Meso-scale topological cues influence extracellular matrix production in a large deformation, elastomeric scaffold model.

D’Amore, A., Nasello, G., Luketich, S.K., Denisenko, D., Jacobs, D.L., Hoff, R., Gibson, G., Bruno, A., Raimondi, M.T. and Wagner, W.R.,

Soft Matter, 14(42), pp.8483-8495. (doi 10.1039/c8sm01352g)


Professional activities and achievements.

Throughout my studies I was driven by the willingness of maturating research experience as a tissue engineer, that led me to join as a visiting researcher the McGowan Institute for Regenerative Medicine, University of Pittsburgh (USA). There, I gained experience in the fabrication and structural characterization of engineered scaffolds for cardiovascular regeneration.



– KU Leuven (September 2020 – Ongoing)

– Materialise  (January 2019 – September 2020)

– The Robert Jones and Agnes Hunt Orthopaedic Hospital (August 2019)

– NUI Galway (February 2018 – April 2018)

– University of Zaragoza (September 2017 – December 2018)