Dr. Industrial Engineer.
José Manuel García Aznar .
BSc in Mechanical Engineering, University of Zaragoza, Spain (1995). PhD in Computational Mechanics from the University of Zaragoza; Thesis work on computational simulation of bone remodeling (1999). Post-doctorate fellow at the Center for Science and Technology in Medicine, University of Keele, United Kingdom (2001), working on computational simulation of tissue differentiation in bone fracture healing. Currently, Full Professor of the Department of Mechanical Engineering in the University of Zaragoza.
Profile
ICoMICS
2022-2026
Individual and Collective Migration of the Immune Cellular System.
European Research Agency
ERC-2020-Advanced Grant (GA Nr 101018587).
VASTO
2023-2025
VAScularised Tumour Organoids on a chip with human placenta vessels as a preclinical model for anticancer therapies.
European Research Agency
ERC-2023-POC (GA Nr 101138214).
METASTRA
2023-2028
Computer-Aided Effective Fracture Risk Stratification of Patients with Vertebral Metastases for Personalised Treatment through Robust Computational Models Validated in Clinical Settings
European Union
HORIZON-HLTH-2022-TOOL-12-01-two-stage (GA Nr 101080135).
Tumatrix-Modeling
2022-2025
Predictive modeling and simulation of patient-derived tumor organoids: unraveling the role of matrix stiffness and glucose metabolism on tumor growth.
National Research Agency
Spain (PID2021-122409OB-C21).
Tumor-on-chip
2019-2021
Microfluidics, mechanobiology and image analysis for 3D tumor growth simulation.
National Research Agency
Spain (RTI2018-094494-B-C21).
Primage
2018-2022
Predictive insilico multiscale analytics to support cancer personalized diagnosis and prognosis, empowered by imaging biomarkers.
European Union
H2020-SC1(Health),(GA 826494).
Curabone
2011-2021
Predictive models and simulations in bone regeneration: a multiscale patient-specific approach.
European Union
H2020-REA MSCA ITN, (GA 722535).
Insilico-cell
2012-2016
Predictive modelling and simulation in mechano-chemo-biology: a computer multi-approach.
European Research Council Starting Grant
Project Number: 306571
Cad-bone
2012-2016
Patient-specific predictions for bone treatments. Marie Curie Actions—Industry-Academia Partnerships and Pathways (IAPP)
In collaboration with Materialise and KU Leuven
Computational mechanics:
- Non-linear FEA
- Multiscale and Multiphysics Analysis
- Discrete models
Computational mechanobiology:
- Mechanics of hard tissues
- Implant design and testing
- Mechanobiology of skeletal tissue regeneration
- Computer tissue engineering
- Tissue growth and development
- Cell mechanics and mechanotransduction
- Cell migration: microfluidics
Self-healing materials:
- Expansive clays
Full list of publications available here
Nasello, G., Alamán-Díez, P., Schiavi, J., Pérez, M. Á., McNamara, L., & García-Aznar J.M.
Frontiers in Bioengineering and Biotechnology, 8, 336.
2020
Kainz H, Killen BA, Wesseling M, Perez-Boerema F, Pitto L, Garcia Aznar JM, Shefelbine S, Jonkers
PLoS One, 15(7): e0235966.
2020
Jorba I, Beltrán G, Falcones B, Suki B, Farré R, García-Aznar JM, Navajas D
Acta Biomater. 92:265-276.
2019
Cóndor M, Mark C, Gerum RC, Grummel NC, Bauer A, García-Aznar JM, Fabry B.
Biophys J. 116(7):1305-1312.
2019
Escribano J, Chen MB, Moeendarbary E, Cao X, Shenoy V, Garcia-Aznar JM, Kamm RD, Spill F.
PLoS Comput Biol. 15(5):e1006395.
2019
Olivares V, Cóndor M, Del Amo C, Asín J, Borau C, García-Aznar JM
Microsc Microanal. 25(4): 971-981.
2019
Movilla N, Valero C, Borau C, García-Aznar JM
Integr Biol (Camb). 11(11) : 404-413.
2019
Hervas-Raluy S, Garcia-Aznar JM, Gomez-Benito MJ
Biomech Model Mechanobiol. 18(4) : 1177-1187.
2019
Valero C, Amaveda H, Mora M, García-Aznar JM
PLoS One. 13(4) : e0195820.
2018
Merino-Casallo F, Gomez-Benito MJ, Juste-Lanas Y, Martinez-Cantin R, Garcia-Aznar JM
Sci Rep. 8(1) : 12723.
2018
Plou J, Juste-Lanas Y, Olivares V, Del Amo C, Borau C, García-Aznar JM
Front Physiol.9: 1246.
2018
Oria, R., Wiegand, T., Escribano, J., Elosegui-Artola, A., Uriarte, J. J., Moreno-Pulido, C., Platzman I, Delcanale P, Albertazzi L, Navajas D, Trepat J, García-Aznar JM, Ada Cavalcanti-Adam E, Roca-Cusachs P
Nature, 552(7684) , 219-224.
2017
Sunyer R, Conte V, Escribano J, Elosegui-Artola A, Labernadie A, Valon L, Navajas D, García-Aznar J.M., Muñoz JJ, Roca-Cusachs P, Trepat X.
Science, 353(6304), 1157-1161.
2016
Rüberg, T., & García-Aznar, J. M.
Engineering Sciences, 3(1), 1
2016
Ribeiro, F. O., Gómez-Benito, M. J., Folgado, J., Fernandes, P. R., & García-Aznar, J. M
Computer Methods in Biomechanics and Biomedical Engineering, 1-16.
2016
Professional activities and achievements.
- Vice-President of the European Society of Biomechanics (2008-2012).
- Associate Director of the Biomedical Engineering Division of I3A (Aragón Institute of Engineering Research).
- Director Board Member of the Virtual Physiological Human Institute.
- Editorial Board membership of Computer Modeling in Engineering and Sciences (2019-), Computer Methods in Biomechanics and Biomedical Engineering (2019-), Computational Particle Mechanics (2014-), PlosOne (2014-) and Bone (2011-).
- Juan C. Simo Young Investigator Award by SEMNI (2004).