Bachelor of Science in Biology

Nieves Movilla Meno.

Position: Research technician and PhD candidate in Biochemistry and Molecular Biology
Phone:

(+34) 876 555 461

Email:

nmovilla@unizar.es

Research technician and PhD candidate in Biochemistry and Molecular Biology

Profile

  • Cell migration
  • Microfluidics
  • Cancer research

The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and tractions at the leading edge of cancer invasion.

María Anguiano, Xabier Morales, Carlos Castilla, Alejandro Rodríguez Pena, Cristina Ederra, Martín Martínez, Mikel Ariz, Hippolyte Amaveda, Mario Mora, Nieves Movilla, José Manuel García Aznar, Iván Cortés Domínguez, Carlos Ortiz-de-Solorzano.

Plos One, January 16, 2020.

2020

Matrix degradation regulates osteoblast protrusion dynamics and individual migration.

Nieves Movilla, Clara Valero, Carlos Borau, JM. García-Aznar

Integrative Biology, 2020, 00(00), 1-10.

2020

Degradation of extracelular matrix regulates osteoblast migration: a microfluidic-based study.

N. Movilla, C. Borau, C. Valero and J.M. García-Aznar.

Bone, 107: 10-17.

2017

A workbench for Biomedical Applications Based on Image Analysis.

Carlos Borau, Cristina del Amo, Jesús Asín, Nieves Movilla, Mar Condor, and José Manuel García-Aznar.

Lecture Notes in Computational Vision and Biomechanics book series (LNCVB, volume 27)

2017

Quantifying 3D chemotaxis in microfluidic-based chips with step gradients of collagen hydrogel concentrations.

C. Del Amo, C. Borau, N. Movilla, Jesús Asín and J.M García-Aznar.

Integrative Biology, Apr 18; 9 (4):339-349.

2017

Fibroblast Migration in 3D is controlled by haptotaxis in a Non-muscle myosin II dependent manner.

O. Moreno-Arotzena, C. Borau, N. Movilla, M. Vicente-Manzanares and J.M. García-Aznar.

Annals of Biomedical Engineering, Dec: 43(12):3025-39

2015

Five entry points of the mitochondrially encodes subunits in mammalian complex I assembly.

Ester Perales-Clemente, Erika Fernández-Vizarra, Rebeca Acín-Pérez, Nieves Movilla, María Pilar Bayona-Bafaluy, Raquel Moreno-Loshuertos, Acisclo Pérez- Martos, Patricio Fernández-Silva and José Antonio Enríquez

Mol.Cell. Biol.30(12):3038-3047.

2010

Cyclosporine A-Induced Nitration of Tyrosine 34 MnSOD in Endothelial Cells: Role of Mitochondrial Superoxide.

Redondo-Horcajo M, Romero N, Martínez-Acedo P, Martínez-Ruiz A, Quijano C, Lourenco CF, Movilla N, Enríquez JA, Rodríguez-Pascual F, Rial E, Radi R, Vázquez J, Lamas S.

Cardiovasc Res.  87(2):356-365.

2010

Functional genetic analysis of the mammalian mitochondrial DNA encoded peptides: a mutagenesis approach.

Bayona-Bafaluy, MP, Movilla N, Fernandez-Silva P, Perez-Martos A, Enriquez JA.

Methods Molecular Biology 457: 379-390.

2007

Reactive oxygen species and the segregation of mtDNA sequence variants.

Moreno-Loshuertos R, Acín-Pérez R, Fernández-Silva1 P, Movilla N, Pérez Martos A, Rodriguez de Cordoba S, Gallardo ME and Enríquez JA

Nature Genetics 39:571-572.

2007

Differences in ROS production provide a molecular explanation for the phenotypes associated to common mouse mitochondrial DNA variants. Reactive oxygen species and the segregation of mtDNA sequence variants.

Moreno-Loshuertos R, Acín-Pérez R, Fernández-Silva1 P, Movilla N, Pérez Martos A, Rodriguez de Cordoba S, Gallardo ME and Enríquez JA

Nature Genetics 39:571-572.

2006

The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.

Agazie, Y.N., Movilla, N., Ischenko, I. and Hayman, M.J.

Oncogene 22: 6909-6918.

2003

Structural determinants for the biological activity of Vav proteins.

Zugaza, J.L., Lopez-Lago, M.A., Caloca, M.J., Dosil, M., Movilla, N., and Bustelo, X.R

J. Biol. Chem. 277:45377-45392.

2002

How Vav proteins discriminate the GTPases Rac1 and RhoA from Cdc42.

Movilla, N., Dosil, M. Zheng, Y., and Bustelo, X.R.

Oncogene 20, 8057-8065.

2001

Tyrosine phosphorylation mediates both activation and down modulation of the biological activity of Vav.

Lopez-Lago, M., Lee, H., Cruz, C., Movilla, N., and Bustelo, X.R.

Mol. Cell. Biol. 20, 1678-1691.

2000

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2.

Schuebel, K.E., Movilla, N., Rosa, J.L., and Bustelo, X.R.

EMBO J. 17, 6608-6621

1998

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins.

Movilla, N. and Bustelo, X.R.

Mol. Cell. Biol.19, 7870-7885.

1999

Signal transduction elements of TC21, an oncogenic member of the R-RAS subfamily of GTP- binding proteins.

Movilla, N.,Crespo,  P. and Bustelo,  X.R.

Oncogene 18, 5860-5869.

1999